The Learning Lead – Volume 3, Issue 1 2020 - Beneficial Effects of sn-2 Palmitate on Early Childho

5 min read /
Gastroenterology Gut health Nutrition & Disease Management
The Learning Lead – Volume 3, Issue 1 2020 - Beneficial Effects of sn-2 Palmitate on Early Childhood Health

Palmitic acid is a common saturated fatty acids found in breast milk, and an important energy source for a rapidly growing infant.

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Reference

  1. Koletzko B, et al. Physiological aspects of human milk lipids and implications for infant feeding: a workshop report. Acta Paediatr. 2011;100(11):1405–1415.
  2. Miles EA, Calder PC. The influence of the position of palmitate in infant formula triacylglycerols on health outcomes. Nutr Res. 2017;44:1–8.
  3. Bronsky J, et al. Palm Oil and Beta-palmitate in Infant Formula: A Position Paper by the European Society for Paediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2019;68(5):742– 760.
  4. Carnielli VP, et al. Structural position and amount of palmitic acid in formulas: effects on fat, fatty acid, and mineral balance. J Pediatr Gastroenterol Nutr. 1996;23:554–60.
  5. Kennedy K, et al. Double-blind, randomized trial of a synthetic triacylglycerol in formula-fed term infants: effects on stool biochemistry, stool characteristics, and bone mineralization. Am J Clin Nutr. 1999;70(5):920–927.
  6. Litmanovitz I, Bar-Yoseph F, Lifshitz Y, et al. Reduced crying in term infants fed high beta-palmitate formula: a double-blind randomized clinical trial. BMC Pediatr. 2014;14:152.
  7. Yaron S, et al. Effect of high β-palmitate content in infant formula on the intestinal microbiota of term infants. J Pediatr Gastroenterol Nutr. 2013;56:376–81.
  8. Lu P, et al. High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice. PLoS One. 2013;8:e65878.

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