Boost Immunity and Gut Health with Nucleotides

5 min read /
Gastroenterology General Nutrition Immunology Paediatrics Gut health Healthy Eating & Hydration
Boost Immunity and Gut Health with Nucleotides

The infographic presents the beneficial effects of nucleotide supplementation on the immune function and gastrointestinal function of infants and children.

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Reference

1Hall, J., 2010. Guyton and Hall Textbook of Medical Physiology 12th ed USA. Saunders.
2Thompson, J., et.al, 2011. The Science of Nutrition 2nd ed. Pearson Education, Inc. USA. 
3Cilla, A., et.al., 2012. Prebiotics and nucleotides in infant feeding; Review of the Evidence. Nutricion Hospitalaria. vol.27 n.4 Jul./Aug. 2012 http://dx.doi.org/10.3305/nh.2012.27.4.5811
4Che L, Hu L, Liu Y, Yan C, Peng X, Xu Q, et al. 2016. Dietary Nucleotides Supplementation Improves the Intestinal Development and Immune Function of Neonates with Intra-Uterine Growth Restriction in a Pig Model. PLoS ONE 11(6):e0157314.doi:10.1371/journal.pone.0157314.
5Gutierrez-Castrellon, P, et. al., 2007. Immune response to nucleotide-supplemented infant formulae: systematic review and meta-analysis. British Journal of Nutrition 98, Suppl. 1, S64–S67 doi: 10.1017/S000711450783296X.
6Carver, J., 2003. Advances in nutritional modifications of infant formulas American Journal of Clinical Nutrition 2003;77(s):1550S–4S. ,http://doi.org/10.1093/ajc n/77.6.1550.
7Jonas, D. et.al., 2001. Safety Considerations of DNA in Food Ann Nutr Metab 45:235–254. 
8Dancey, C. et.al., 2006. Nucleotide supplementation: a randomised double-blind placebo controlled trial of IntestAidIB in people with Irritable Bowel Syndrome [ISRCTN67764449] Nutrition Journal 5:16 doi:10.1186/1475-2891-5-16.
9Carver, J., 1994. Dietary Nucleotides: Cellular Immune, Intestinal and Hepatic System Effects. The Journal of Nutrition, 124(s1):144S–148S, https://doi.org/10.1093/jn/124.suppl_1.144S.
10Eckhard Schlimme, E., et. al., 2000. Nucleosides and nucleotides: natural bioactive substances in milk and colostrum. British Journal of Nutrition , 84:S1, S59±S68. https://doi.org/10.1017/S0007114500002269.
11Lerner, A. & Shamir, R., 2000. Nucleotides in Infant Nutrition: A Must or an Option. IMAJ;2:772–774.
12Gil, A., 2002. Modulation of the immune response mediated by dietary nucleotides. European Journal of Clinical Nutrition 56(3),S1–S4. doi:10.1038=sj.ejcn.1601475 (journal review).

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